Teaching Video NeuroImage: Foix−Chavany−Marie syndrome
Peter L. Konieczny, Benjamin H. Eidelman and William D. Freeman
Neurology 2008;70;e88
DOI 10.1212/01.wnl.0000312516.55722.dd
This information is current as of May 19, 2008

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RESIDENT
& FELLOW
SECTION
Section Editor
Mitchell S.V. Elkind,
MD, MS

Peter L. Konieczny,
MD
Benjamin H.
Eidelman, MD, PhD
William D. Freeman,
MD

Address correspondence and
reprint requests to Dr. William
D. Freeman, Department of
Neurology, Mayo Clinic, 4500
San Pablo Road, Jacksonville,
FL 32224
freeman.william1@mayo.edu

Teaching Video NeuroImage:
Foix–Chavany–Marie syndrome

A 79-year-old woman with a history of prior
right frontal infarction presented with sudden
inability to speak (figure, A). Examination revealed anarthria, yet intact comprehension,
writing, and limb function (video). Voluntary
tongue, swallowing, and mouth movements
were absent, while cough and swallow reflexes
were preserved (video). An acute left hemispheric ischemic stroke causing Foix-ChavanyMarie syndrome (FCMS) was diagnosed, and
IV recombinant tissue plasminogen activator
was administered. Left frontal infarction was
confirmed on MRI (figure, B).
FCMS involves lesions of the bilateral frontal
operculum1 or the cortical-subcortical areas of

Figure

REFERENCES
1.
Foix C, Chavany J-A, Marie J. Diplégie facio-linguomasticatrice d’origine cortico sous-corticale sans
paralysie des membres (contribution à l’étude de la localisation des centres de la face du membre supérieur),
par MM. Rev Neurol 1926;33:214–219.
2.
Weller M. Anterior opercular cortex lesions cause dissociated lower cranial nerve palsies and anarthria but
no aphasia: Foix-Chavany-Marie syndrome and “automatic voluntary dissociation” revisited. J Neurol 1993;
240:199–208.

(A) CT scan without contrast showing area of old right-sided infarct
encompassing the frontoparietal opercular cortex; (B) diffusionweighted MRI with restricted diffusion in the left precentral gyrus

Supplemental data at
www.neurology.org
From the Department of Neurology, Mayo Clinic, Jacksonville, FL.
Disclosure: The authors report no disclosures.
e88

primary motor cortex.2 Voluntary control of
facio-pharyngo-glosso-masticatory muscles is
lost, while reflex movements and limb strength
are preserved.

Copyright © 2008 by AAN Enterprises, Inc.

Teaching Video NeuroImage: Foix−Chavany−Marie syndrome
Peter L. Konieczny, Benjamin H. Eidelman and William D. Freeman
Neurology 2008;70;e88
DOI 10.1212/01.wnl.0000312516.55722.dd
This information is current as of May 19, 2008
Updated Information &
Services

including high resolution figures, can be found at:
http://www.neurology.org/content/70/21/e88.full.html

Supplementary Material

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http://www.neurology.org/content/suppl/2008/05/16/70.21.e88.D
C1.html

References

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http://www.neurology.org/content/70/21/e88.full.html##ref-list-1

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