RESIDENT & FELLOW SECTION Section Editor Mitchell S.V. Elkind, MD, MS Bernhard Suter, MD Lisa Michael El-Hakam, MD Child Neurology: Stroke due to nontraumatic intracranial dissection in a child Figure MRI and catheter angiography Address correspondence and reprint requests to Dr. Lisa Michael El-Hakam, Department of Pediatric Neurology, Baylor College of Medicine, Texas Children’s Hospital, 6621 Fannin St. CC 1250, Houston, TX 77030-2399 hakam@bcm.edu (A, B) Diffusion-weighted sequence of MRI of the brain shows acute infarction in the right middle cerebral artery (MCA) territory. (C, D) Catheter angiography showed irregularities of the right supraclinoid internal carotid artery, extending into the M1 segment of the right MCA. An intimal flap (arrow) indicates dissection. A 9-year-old girl without prior trauma presented with weakness and headache. Examination showed profound left hemiplegia. MRI demonstrated a right middle cerebral artery (MCA) territory infarction. Magnetic resonance angiography showed proximal right MCA irregularity. Conventional angiography revealed an intracranial dissection (figure). Intracranial dissections are frequently spontaneous (nontraumatic) and are associated with stroke in the young, comprising 60% of anterior circulation dissections in childhood.1 Exclusion of intracranial dissections is challenging using magnetic resonance angiography; cerebral angiography must be consid- ered.2 Potential treatments include anticoagulation and antiplatelet therapies; Class III recommendations discourage anticoagulation because of the association of subarachnoid hemorrhage with intracranial dissection.2 REFERENCES 1. Fullerton HJ, Johnston SC, Smith WS. Arterial dissection and stroke in children. Neurology 2001;57:1155–1160. 2. Roach ES, Golomb MR, Adams R, et al. Management of stroke in infants and children: a scientific statement from a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young. Stroke 2008;39:2644–2691. From the Department of Pediatric Neurology, Texas Children’s Hospital, Baylor College of Medicine, Houston. Disclosure: The authors report no disclosures. e100 Copyright © 2009 by AAN Enterprises, Inc. Child Neurology: Stroke due to nontraumatic intracranial dissection in a child Bernhard Suter and Lisa Michael El-Hakam Neurology 2009;72;e100 DOI 10.1212/WNL.0b013e3181a55f52 This information is current as of May 11, 2009 Updated Information & Services including high resolution figures, can be found at: http://www.neurology.org/content/72/19/e100.full.html References This article cites 2 articles, 2 of which you can access for free at: http://www.neurology.org/content/72/19/e100.full.html##ref-list-1 Subspecialty Collections This article, along with others on similar topics, appears in the following collection(s): All Cerebrovascular disease/Stroke http://www.neurology.org//cgi/collection/all_cerebrovascular_disease_ stroke Carotid artery dissection http://www.neurology.org//cgi/collection/carotid_artery_dissection Childhood stroke http://www.neurology.org//cgi/collection/childhood_stroke Permissions & Licensing Information about reproducing this article in parts (figures,tables) or in its entirety can be found online at: http://www.neurology.org/misc/about.xhtml#permissions Reprints Information about ordering reprints can be found online: http://www.neurology.org/misc/addir.xhtml#reprintsus Neurology ® is the official journal of the American Academy of Neurology. Published continuously since 1951, it is now a weekly with 48 issues per year. Copyright . All rights reserved. Print ISSN: 0028-3878. Online ISSN: 1526-632X.