□ PICTURES IN CLINICAL MEDICINE □ Intravenous t-PA for the Occlusion of an Accessory MCA Hiroya Kuwahara, Ken Matsumura, Mutsufusa Watanabe and Hiroto Fujigasaki Key words: intravenous tissue plasminogen activator, accessory middle cerebral artery, magnetic resonance angiography, cerebral angiography (Intern Med 52: 163, 2013) (DOI: 10.2169/internalmedicine.52.8999) potential causes of ischemic stroke were identified, such as cardiovascular disturbances or coagulation disorders. An accessory MCA is an anomalous vessel originating from the anterior cerebral artery. The frequency of this anomaly is reported to range from 0.3% to 4.0% (1). Aneurysms are an occasional complication of accessory MCAs (2), but ischemic strokes associated with this type of artery are extremely rare (3, 4). Thrombosis might have been induced by blood turbulence in the proximal portion of the accessory MCA in our patient. The authors state that they have no Conflict of Interest (COI). Acknowledgement We thank Dr. Keiko Nakamura (Junior resident, Tokyo Metropolitan Bokutoh Hospital) and Dr. Kazuo Hanakawa (Department of Neurosurgery, Tokyo Metropolitan Bokutoh Hospital) for their valuable clinical assistance. References Picture. A 27-year-old man suddenly developed severe left hemiplegia and dysarthria. Magnetic resonance angiography showed the occlusion of the right accessory middle cerebral artery (MCA) (Picture A). The symptoms fully recovered after the intravenous administration of tissue plasminogen activator (t-PA). Cerebral angiography performed after the treatment revealed recanalization of the artery (Picture B). No 1. Komiyama M, Nakajima H, Nishikawa M, Yasui T. Middle cerebral artery variations: duplicated and accessory arteries. AJNR Am J Neuroradiol 19: 45-49, 1998. 2. Reis CV, Zabramski JM, Safavi-Abbasi S, Hanel RA, Deshmukh P, Preul MC. The accessory middle cerebral artery: anatomic report. Neurosurgery 63 (ONS Suppl 1): 10-14, 2008. 3. Gao F, Jiang WJ. Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report. Clin Neurol Neurosurg 111: 588-590, 2009. 4. Menon BK, Aaron S, Bal S, Hill MD, Demchuk AM, Goyal M. Acute embolic occlusion of the accessory middle cerebral artery mimicking an internal carotid artery terminus aneurysm. Neurol India 59: 908-909, 2011. Department of Neurology, Tokyo Metropolitan Bokutoh Hospital, Japan Received for publication October 1, 2012; Accepted for publication October 9, 2012 Correspondence to Dr. Hiroya Kuwahara, h-kuwahara.nuro@tmd.ac.jp Ⓒ 2013 The Japanese Society of Internal Medicine Journal Website: http://www.naika.or.jp/imonline/index.html 163