Asymptomatic Intracerebral Hematoma as an Incidental Finding Richard A. Rudick, MD Tntracerebral hemorrhage is being diagnosed with increasing frequency in less severely ill "stroke" patients.1-3 An unexpected basal gan- glia hemorrhage was diagnosed by computed tomographic (CT) scan in an asymptomatic 59-year-old woman. The scan was obtained as part of the diagnostic evaluation of a seizure disorder of 18 years' duration. This further expands the clinical spectrum of intracerebral hematoma. Fig 2—Scan obtained seven days after in Fig 1 shows hematoma partially resolved, with surrounding edema. scan REPORT OF A CASE A 59-year-old right-handed woman came to the Strong Memorial Hospital Neurology Clinic, Rochester, NY, in January 1978 for evaluation of a seizure disorder. Her seizures began at age 41 years and were of the partial-complex type, with alteration of consciousness and motor automatisms. Sei- phenytoin sodium, phenobarbital, and primidone. Several EEGs showed paroxysmal bitemporal slowing. She had a long history of treated hypertension, chronic renal failure, adezures were controlled with quately treated syphilis (with a negative CSF VDRL), severe degenerative joint disease, and marked obesity. In searching for a lesion that was responsible for her seizure disorder, a CT scan was done. On Feb 1, 1978, a routine outpatient CT scan of the head, without contrast enhancement, showed a small left basal ganglia hematoma, without signifi¬ cant mass effect or midiine shift (Fig 1). Later that day the patient was unavailable because she had gone shopping. On Feb 2 she declined to return because she was feeling well. She denied headache, seizures, or nausea. On Feb 8 she came to the clinic on the urging of her physician. Other than slight lethargy, unilateral asterixis, and minimal¬ ly slowed movements of her right upper extremity, she had no abnormal neurologic signs. Her blood pressure was 200/120 mm Hg. A second CT scan on Feb 8 showed the hematoma to be slightly larger but of decreased density, again without shift of midiine structures (Fig 2). She was admit¬ ted for observation. Her blood level of phénobarbital was 41 /ng/mL; with reduc- Accepted for publication Sept 28, 1980. From the Department of Neurology and Center for Brain Research, University of Rochester School of Medicine and Dentistry, Rochester, NY. Reprint requests to Department of Neurology, Strong Memorial Hospital, The University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642 (Dr Rudick). Fig 1.—Left basal ganglia hemorrhage. Fig 3—Scan obtained 17 days after scan in Fig 1 shows complete resolution of blood density but some residual edema. tion of dosage, her mental state quickly returned to normal and her asterixis and slowed right arm movement quickly resolved. On Feb 17 a third CT scan showed reso¬ lution of the intracerebral hematoma, with some residual decreased density thought to represent edema (Fig 3). She has since had only occasional partial-complex seizures and intermittent symptoms of uremia. COMMENT In this patient, a CT scan was done as part of an évaluation of a seizure disorder; the finding of a fresh, small basal ganglia hemorrhage was unex¬ pected. In fact, the patient came to the hospital alone by bus, and follow¬ ing her CT scan went shopping. She felt well during the entire time sur¬ rounding the hemorrhage. Computed tomographic scanning is highly sensitive in detection of small hemorrhages. Computed tomographic findings of intracerebral hemorrhage" ' and patterns associated with hemor¬ rhages in various locations have been described.7 However, the occurrence of a clinically unnoticed intracerebral hemorrhage diagnosed by CT scan done for other reasons has not been previously recorded. This case demonstrates that clini¬ cally unnoticed intracerebral hemor¬ rhage can occur, and may be more frequent than is appreciated. References 1. Pineda A: Computed tomography in intracerebral hemorrhage. Surg Neurol 1977;8:55-58. 2. Caplan R, Mohr JP: Intracerebral hemorrhage: An update. Geriatrics 1978;33:42-45, 48\x=req-\ 52. 3. Herman T, Satya-Murti S: Benign cerebellar hemorrhages. Ann Neurol 1978;3:366-368. 4. Scott WR, New PFJ, Davis KR, et al: Computerized axial tomography of intracerebral and intraventricular hemorrhage. Radiology 1974;112:73-80. 5. Hayward RD, O'Reilly GVA: Intracerebral hemorrhage. Lancet 1976;1:1-4. 6. Weisberg LA: Computerized tomography in Intracranial hemorrhage. Arch Neurol 1979;36:422-426. 7. Ojemann RG, Mohr JP: Hypertensive brain hemorrhage. Clin Neurosurg 1975;23:220-244. Downloaded From: http://archneur.jamanetwork.com/ by a Penn State Milton S Hershey Med Ctr User on 05/22/2015